Xp (short-arm) genes: Deletions otherwise interruptions out of crucial regions of the latest short-arm off the newest X chromosome (Xp11, Xp22.1-21.3) was described in association with gonadal dysgenesis and you may prienorrhea.

Zfx (X-connected zinc finger protein): Situated on Xp22.1-21.step 3, so it gene encodes a generally shown protein away from not familiar setting. Zfx “knockout” mice is short, smaller fruitful, and get a lowered germ cell number on ovaries and you can testes.

USP9X gene (ubiquitin-particular protease nine gene): It’s found on Xp11.cuatro, and its own product is widely expressed in many architecture. Inside the Drosophila, USP9X needs to own vision advancement and oogenesis, however, their role inside the people gonadal creativity are uncertain.

Xq (long-arm) genes: Analysis out-of critical deletions and autosomal translocations produced information on the new importance of several section on the long-arm of one’s X chromosome. They truly are Xq13-21, Xq22-twenty five, and you can Xq26-twenty-eight.

FMR1 gene: Which gene is to your Xq27.step three. Continuar lectura →